๐Ÿ” CVE Alert

CVE-2026-31965

UNKNOWN 0.0

HTSlib CRAM reader has out-of-bounds reads due to improper validation of input

CVSS Score
0.0
EPSS Score
0.0%
EPSS Percentile
0th

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the `cram_decode_slice()` function called while reading CRAM records, validation of the reference id field occurred too late, allowing two out of bounds reads to occur before the invalid data was detected. The bug does allow two values to be leaked to the caller, however as the function reports an error it may be difficult to exploit them. It is also possible that the program will crash due to trying to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

CWE CWE-125 CWE-129
Vendor samtools
Product htslib
Published Mar 18, 2026
Last Updated Mar 19, 2026
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Affected Versions

samtools / htslib
< 1.21.1 >= 1.22, < 1.22.2 = 1.23

References

NVD โ†— CVE.org โ†— EPSS Data โ†—
github.com: https://github.com/samtools/htslib/security/advisories/GHSA-mqm2-v645-3qhr github.com: https://github.com/samtools/htslib/commit/9cefb46453ad471e933b8212d4f45920524d3357